Exclusively licensed and manufactured for: Evolus, Inc., 520 Newport Center Drive, Suite 1200, Newport Beach, CA 92660
US-JUV-2200306
Ready for a
modern-made tox?
Those lines between your brows can be optional with FDA-approved Jeuveau® (prabotulinumtoxinA-xvfs).
As Seen In
Modern-made using Hi-Pure™ Technology
Jeuveau® stops your nerves from telling your facial muscles to flex, temporarily smoothing moderate to severe lines between the brows.
Do not use Jeuveau® if you are allergic to any of its ingredients, have had an allergic reaction to any other botulinum toxin product, or have a skin infection at the planned injection site.
Smooth Frown Lines
Quick, 10-minute treatment1
Natural Looking1
Modern-made using Hi-Pure™ Technology, Jeuveau® temporarily smooths the appearance of moderate to severe frown lines.
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Jeuveau® is a prescription medicine that is injected into muscles and used in adults for a short period of time (temporary) to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines).
Jeuveau® dosing units are not the same as, or comparable to, any other botulinum.
1. Jeuveau® Experience Treatment patient survey data collected 30 days after treatment, December 2019 (n=9,151); 95% rated results with Jeuveau® as natural-looking; Somewhat to strongly agreed on a 5-point rating scale
In a study conducted in Europe and Canada, 54% of patients had a ≥1-grade improvement in frown lines at Day 2 based on physician assessment compared to 12% for placebo (secondary endpoint).1 In US studies, 46% and 56% had a ≥1-grade improvement in frown lines at Day 2 based on physician-assessment compared to 8% and 17% for placebo (exploratory endpoint).2 Results based on a 1-grade improvement may not be considered clinically meaningful.
In two US studies, the overall efficacy of Jeuveau® was evaluated using a 2-grade or better physician- and patient-rated improvement in frown lines at Day 30 at 68% and 70%, respectively, compared to 1% for placebo.2
In a study conducted in Europe and Canada, 38% of patients had a ≥1-grade improvement in frown lines at 5 months based on physician assessment compared to 8% for placebo (secondary endpoint).1 In US studies, almost 5% of patients had a ≥2-grade improvement in frown lines at 5 months based on both patient and physician assessments compared to 0% for placebo (secondary endpoint).2 Results after day 30 or based on a 1-grade improvement may not be clinically meaningful.
Jeuveau® is a prescription medicine that is injected into muscles and used in adults for a short period of time (temporary) to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines).
Before treatment with Jeuveau®, tell your healthcare provider about all of your medical conditions, including: any muscle or nerve conditions, side effects from botulinum toxin products, breathing, swallowing, bleeding, or heart problems; plans to have surgery; weakness of forehead muscles; drooping eyelids; have had surgery on your face; are pregnant or breastfeeding or plan to become pregnant or breastfeed.
Jeuveau®
modern-made tox
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using Jeuveau® with certain other medicines may cause serious side effects.
Lines happen.
Do something about it today! Jeuveau® is a prescription medicine that is injected into muscles to temporarily improve the look of moderate to severe frown lines between the eyebrows in adults
- Rzany B. A multicenter, randomized, double-blind, placebo-controlled, single-dose, phase III, non-inferiority study comparing prabotulinumtoxinA and onabotulinumtoxinA for the treatment of moderate to severe glabellar lines in adult patients. Aesthet Surg J. 2020;40(4):413-429.
- Beer K. Efficacy and safety of prabotulinumtoxinA for the treatment of glabellar lines in adult subjects: results from 2 identical phase III studies. Dermatol Surg. 2019;45(11):1381-1393.
IMPORTANT SAFETY INFORMATION FOR JEUVEAU® (prabotulinumtoxinA-xvfs)
JEUVEAU® may cause serious side effects that can be life threatening. Get medical help right away if you have any of these problems any time (hours to weeks) after injection of JEUVEAU®:
• Problems swallowing, speaking, or breathing, due to weakening of associated muscles, can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection. Swallowing problems may last for several months.
• Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, trouble swallowing.