Prescribing Information Medication Guide

Exclusively licensed and manufactured for: Evolus, Inc., 520 Newport Center Drive, Suite 1200, Newport Beach, CA 92660

PDCR 2020-02-005

Ready for a
modern-made tox?

Thanks to FDA approval, those lines between your brows can be optional with Jeuveau®.

FDA-Approved

Jeuveau® is a prescription medicine that is injected into muscles and used in adults for a short period of time (temporary) to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines).

As Seen In

Modern-made using Hi-Pure™ Technology

Jeuveau® stops your nerves from telling your facial muscles to flex, temporarily smoothing moderate to severe lines between the brows.


Do not use Jeuveau® if you are allergic to any of the ingredients in Jeuveau® such as botulinum toxin type A and human serum albumin

Smooth Frown Lines
Quick, 10-minute treatment1
Natural Looking1

Modern-made using Hi-Pure™ Technology, Jeuveau® temporarily smooths the appearance of moderate to severe frown lines.


Get Started

Jeuveau® is a prescription medicine that is injected into muscles and used in adults for a short period of time (temporary) to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines).

Do not use Jeuveau® if you have had an allergic reaction to any other botulinum toxin products

1. Jeuveau® Experience Treatment patient survey data collected 30 days after treatment, December 2019 (n=9,151); 95% rated results with Jeuveau® as natural-looking; Somewhat to strongly agreed on a 5-point rating scale

In a study conducted in Europe and Canada, 54% of patients had a >1-grade improvement in frown lines at Day 2 based on physician assessment compared to 12% for placebo (secondary endpoint). In US studies, 46% and 56% had a >1-grade improvement in frown lines at Day 2 based on physician-assessment compared to 8% and 17% for placebo (exploratory endpoint). Results based on a 1-grade improvement may not be considered clinically meaningful.

In two US studies, the overall efficacy of Jeuveau® was evaluated using a 2-grade or better physician- and patient-rated improvement in frown lines at Day 30 at 68% and 70%, respectively.

In a study conducted in Europe and Canada, 38% of patients had a >1-grade improvement in frown lines at 5 months based on physician assessment compared to 8% for placebo (secondary endpoint). In US studies, almost 5% of patients had a >2-grade improvement in frown lines at 5 months based on both patient and physician assessments compared to 0% for placebo (secondary endpoint). Results based on a 1-grade improvement may not be considered clinically meaningful.

*JEUVEAU® patient at maximum frown. Individual results may vary

Jeuveau® is a prescription medicine that is injected into muscles and used in adults for a short period of time (temporary) to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines).

Do not use JEUVEAU® if you have a skin infection at the planned injection site.

Say hello,
Jeuveau®
and helloooooo to a
modern-made tox

Tell your healthcare provider about all your medical conditions, including if you have a disease that affects your muscles and nerves or have had any side effects from any botulinum toxin product in the past, plan to become pregnant, are pregnant or breastfeeding


Lines happen.

Do something about it today! Jeuveau® is a prescription medicine that is injected into muscles to temporarily improve the look of moderate to severe frown lines between the eyebrows in adults

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IMPORTANT SAFETY INFORMATION FOR JEUVEAU® (prabotulinumtoxinA-xvfs)

JEUVEAU® may cause serious side effects that can be life threatening. Get medical help right away if you have any of these problems any time (hours to weeks) after injection of JEUVEAU®:
Problems swallowing, speaking, or breathing, due to weakening of associated muscles, can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection. Swallowing problems may last for several months.
Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, trouble swallowing.